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糖链抗原50是一种非特异性的广谱肿瘤标记物，与糖链抗原19-9有一定交叉抗原性，主要用于胰腺癌、结肠癌、直肠癌、胃癌的辅助诊断，其中胰腺癌病人升高最明显。 此过程被称为溶原性转化 (或噬菌体转化)，最早于二十世纪50年代观察到，它描述了前噬菌体提供有利于溶原的额外基因的情况 (图2)。
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