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Left ventricular endocardial pacing and conduction system pacing. Left ventricle (lv) pacing can be considered peculiar due to its different lead/tissue interface (epicardial pacing) and the small vein wedging lead locations with less reliable lead stability. Observational studies have demonstrated their potential
However, several limitations should be addressed. The effect of left ventricular myocardial septal pacing (lvsp) and left bundle branch pacing (lbbp) on ventricular synchrony and lv hemodynamics is poorly understood in unselected cardiac resynchronization therapy (crt) patients. Leadless lv endocardial pacing may provide benefit by delivering more physiological activation patterns, and enabling pacing from optimized lv cavity sites
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